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41.
针对原生FIPA-ACL在装备保障Agent通信中存在的语义描述范围不够、通信效率较低和语义识别不准确的问题,提出了一种基于扩展FIPA-ACL的装备保障Agent通信语言设计与实现方法.首先对FIPA-ACL的通信原语进行了扩充,并给出原语的形式化语义描述方法;其次对装备保障专业领域的通信本体进行了定义,明确了通信内容使用的基本词汇;再次基于FIPA-SL进行了内容语法定义和通信内容描述;最后对装备保障Agent通信语言进行了实现,并在某部队装备保障智能仿真推演与效能评估系统中进行了应用,验证了本文所提出语言的可行性及有效性.  相似文献   
42.
Ferric oxide is one of the key factors affecting both the microstructure and the properties of CaO-MgO-SiO_2-based ceramics. Research on this effect is significant in the utilization of iron-rich solid wastes in ceramics. Ceramic samples with various Fe_2O_3 contents(0 wt%, 5 wt%, and 10 wt%) were prepared and the corresponding physical properties and microstructure were studied. The results indicated that Fe_2O_3 not only played a fluxing role, but also promoted the formation of crystals. Ceramics with 5 wt% of Fe_2O_3 addition attained the best mechanical properties with a flexural strength of 132.9 MPa. Iron ions were dissolved into diopside, consequently causing phase transformation from diopside and protoenstatite to augite, thereby contributing to the enhancement of its properties. An excess amount of Fe_2O_3 addition(10 wt% or more) resulted in deteriorated properties due to the generation of an excess volume of liquid and the formation of high-porosity structures within ceramics.  相似文献   
43.
Random walks are a standard tool for modeling the spreading process in social and biological systems.But in the face of large-scale networks,to achieve convergence,iterative calculation of the transition matrix in random walk methods consumes a lot of time.In this paper,we propose a three-stage hierarchical community detection algorithm based on Partial Matrix Approximation Convergence(PMAC) using random walks.First,this algorithm identifies the initial core nodes in a network by classical measurement and then utilizes the error function of the partial transition matrix convergence of the core nodes to determine the number of random walks steps.As such,the PMAC of the core nodes replaces the final convergence of all the nodes in the whole matrix.Finally,based on the approximation convergence transition matrix,we cluster the communities around core nodes and use a closeness index to merge two communities.By recursively repeating the process,a dendrogram of the communities is eventually constructed.We validated the performance of the PMAC by comparing its results with those of two representative methods for three real-world networks with different scales.  相似文献   
44.
An innovative method for recovering valuable elements from vanadium-bearing titanomagnetite is proposed. This method involves two procedures: low-temperature roasting of vanadium-bearing titanomagnetite and water leaching of roasting slag. During the roasting process, the reduction of iron oxides to metallic iron, the sodium oxidation of vanadium oxides to water-soluble sodium vanadate, and the smelting separation of metallic iron and slag were accomplished simultaneously. Optimal roasting conditions for iron/slag separation were achieved with a mixture thickness of 42.5 mm, a roasting temperature of 1200°C, a residence time of 2 h, a molar ratio of C/O of 1.7, and a sodium carbonate addition of 70 wt%, as well as with the use of anthracite as a reductant. Under the optimal conditions, 93.67% iron from the raw ore was recovered in the form of iron nugget with 95.44% iron grade. After a water leaching process, 85.61% of the vanadium from the roasting slag was leached, confirming the sodium oxidation of most of the vanadium oxides to water-soluble sodium vanadate during the roasting process. The total recoveries of iron, vanadium, and titanium were 93.67%, 72.68%, and 99.72%, respectively.  相似文献   
45.

Introduction

Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets.

Materials and methods

GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC. The pathways connecting GPCR peptide ligands with their receptors were identified by manual searches in the PubMed, IUPHAR and Ingenuity databases. Distribution of PYY protein in mouse and human islets was determined by immunohistochemistry. Insulin, glucagon and somatostatin secretion from islets was measured by radioimmunoassay.

Results

We have quantified GPCR peptide ligand mRNA expression in human and mouse islets and created specific signalomes mapping the pathways by which islet peptide ligands regulate human and mouse GPCR signalling. We also identified species-specific islet expression of several GPCR ligands. In particular, PYY mRNA levels were ~ 40,000-fold higher in mouse than human islets, suggesting a more important role of locally secreted Pyy in mouse islets. This was confirmed by IHC and functional experiments measuring insulin, glucagon and somatostatin secretion.

Discussion

The detailed human and mouse islet GPCR peptide ligand atlases will allow accurate translation of mouse islet functional studies for the identification of GPCR/peptide signalling pathways relevant for human physiology, which may lead to novel treatment modalities of diabetes and metabolic disease.
  相似文献   
46.
系统评价与元分析同属综合研究结果的分析方法,常将元分析作为定量的系统评价。笔者应用系统评价的方法,全面梳理近20年来的相关文献,并将提取的相关信息分类编码整合成数据库,分析、探讨元分析的应用现状和特点。结果发现:漏斗图不仅用于效应分布的描述,更应用于检验小(样本容量或精度)研究有大效应的现象;调节分析与常说的调节效应分析稍有差异,元分析中的调节分析更类似于一般多元回归;发表偏倚的检验方法中,剪补法功效较高于其它方法。结论:元分析的基础理论和实际应用方面相对滞后,数据分析和研究报告等方面亟待规范统一;元分析以后将更多应用于多元统计和认知领域(FMRI和ERP的数据合成分析)等方面。  相似文献   
47.
针对故障在复杂机电产品中传递发展的特点,提出了一种基于动作单元的机电产品故障溯源诊断方法.按照"功能-运动-动作"对整机功能进行结构化分解得到基本的动作单元,并分析动作单元之间的传递过程;在此基础上建立以动作单元和故障现象为节点的贝叶斯网络模型,利用贝叶斯网络的推理算法,计算各个节点的发生概率并追溯最大概率路径,实现动作层的故障动作单元诊断及故障动作单元传播过程诊断;利用故障图对动作单元内部的故障模式及其传递发展过程进行描述,找到引起动作单元故障的根本原因.通过对机电产品动作层和动作单元内部的诊断分析,实现故障现象到故障原因的溯源诊断.将所提出的溯源诊断方法应用到某企业数控转台故障诊断中,结果表明,从运动的角度进行故障溯源诊断,能够有效地诊断出故障动作单元及其传播过程并反映出动作单元内部元件故障的传递发展过程,便于找到导致故障的根本原因,提高了对机电产品故障诊断的效率.  相似文献   
48.
49.
以广州某污水处理厂的低碳源废水运行为例,探讨了位于北回归线以南气候为亚热带季风气候区域的改良AAO工艺在低碳源进水条件下的优化条件,在尽量避免另加碳源的情况下,通过工艺优化,可以确保正常处理效果。采用多点进水改良的A~2/O工艺取得了较好的脱氮除磷效果,说明了在传统A~2/O工艺厌氧池前增加预缺氧池,而且经过预处理的污水多点分配进入生化池,可以在低碳源条件下,优化生物脱氮除磷效果。研究结果表明,在利用内碳源条件下改良AAO工艺的污泥龄取19天,内回流率取130%,外回流率取80%,出水能稳定达标。试验结果为采用改良AAO工艺的污水处理厂在高原环境下运行提供了参考数据,也可为低碳源情况下污水厂升级改造设计时进行参考。  相似文献   
50.
依托福州地铁六号线滨海新城站—莲花站区间隧道工程,就扩径后的盾构机进行了现场100环掘进试验,分析了掘进参数土压力、刀盘扭矩及其转速、总推力、掘进速度、出土量和同步注浆量,给出了建议值,为今后类似工程提供参考。  相似文献   
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